US 12,384,763 B2
Protein and/or peptide modification molecule
Takashi Hayashi, Osaka (JP); Akira Onoda, Osaka (JP); and Nozomu Inoue, Osaka (JP)
Assigned to OSAKA UNIVERSITY, Osaka (JP)
Appl. No. 17/432,838
Filed by Osaka University, Osaka (JP)
PCT Filed Feb. 28, 2020, PCT No. PCT/JP2020/008357
§ 371(c)(1), (2) Date Aug. 20, 2021,
PCT Pub. No. WO2020/175680, PCT Pub. Date Sep. 3, 2020.
Claims priority of application No. 2019-035340 (JP), filed on Feb. 28, 2019.
Prior Publication US 2022/0204481 A1, Jun. 30, 2022
Int. Cl. C07D 403/12 (2006.01); C07D 249/04 (2006.01); C07D 403/04 (2006.01); C07D 493/10 (2006.01); C07D 495/04 (2006.01)
CPC C07D 403/12 (2013.01) [C07D 249/04 (2013.01); C07D 403/04 (2013.01); C07D 493/10 (2013.01); C07D 495/04 (2013.01)] 4 Claims
 
1. A compound represented by formula (7) or a salt thereof, or a hydrate or solvate of the compound or a salt thereof,

OG Complex Work Unit Chemistry
wherein one of R1 and R2 represents —N(—R4)— (wherein R4 represents an organic group or a group derived from an inorganic material), and the other represents ═N—; R3 represents a hydrogen atom, an organic group, or a group derived from an inorganic material; a double line composed of a dotted line and a solid line represents a single bond or a double bond; R13 represents a group in which the N-terminal amino acid residue and —NH— adjacent thereto are excluded from a protein or peptide and the remaining protein or peptide is bonded through the carbon which was previously bonded to the —NH— adjacent to the N-terminal amino acid residue; and R14 represents the side chain of the N-terminal amino acid residue of the protein or peptide.