US 12,384,738 B2
Production of aromatic acids and phenolics
Marc Crockatt, 's-Hertogenbosch (NL)
Assigned to Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO, 's-Gravenhage (NL)
Appl. No. 17/766,615
Filed by Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO, s-Gravenhage (NL)
PCT Filed Oct. 22, 2020, PCT No. PCT/NL2020/050654
§ 371(c)(1), (2) Date Apr. 5, 2022,
PCT Pub. No. WO2021/080426, PCT Pub. Date Apr. 29, 2021.
Claims priority of application No. 19204640 (EP), filed on Oct. 22, 2019.
Prior Publication US 2024/0067593 A1, Feb. 29, 2024
Int. Cl. C07C 51/265 (2006.01); C07C 37/055 (2006.01)
CPC C07C 51/265 (2013.01) [C07C 37/0555 (2013.01)] 23 Claims
 
1. A method for the preparation of an aromatic acid or a phenolic compound, said method comprising reacting a dienophile and a furanic compound comprising an acetal moiety in a Diels-Alders reaction to obtain an aromatic compound comprising said acetal moiety, followed by hydrolysis and oxidation of said acetal moiety into a hydroxide or carboxylate moiety to form the aromatic acid or phenolic compound, wherein said dienophile is selected from the group consisting of alkylenes, acetylenes, acrylates, maleates, fumarates, maleimides, propiolates, acetylene dicarboxylates, and benzynes and wherein said acetal moiety is bound directly to the 2-position of the furanic compound.