US 12,383,906 B2
Device and method for detection of pathogens
Paul Yager, Seattle, WA (US); Steven Bennett, Seattle, WA (US); Erin K. Heiniger, Seattle, WA (US); Sujatha Kumar, Seattle, WA (US); and Kamal Girish Shah, Seattle, WA (US)
Assigned to University of Washington, Seattle, WA (US)
Filed by University of Washington, Seattle, WA (US)
Filed on Jun. 13, 2022, as Appl. No. 17/838,807.
Claims priority of provisional application 63/210,459, filed on Jun. 14, 2021.
Prior Publication US 2022/0395838 A1, Dec. 15, 2022
Int. Cl. B01L 7/00 (2006.01); B01L 3/00 (2006.01); C12Q 1/6806 (2018.01)
CPC B01L 7/52 (2013.01) [B01L 3/502715 (2013.01); C12Q 1/6806 (2013.01); B01L 2200/10 (2013.01); B01L 2300/0861 (2013.01); B01L 2300/1805 (2013.01); B01L 2400/0457 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A fluidic device comprising:
a housing defining a lysis chamber shaped to receive a biological sample;
a lysis buffer storage chamber disposed within the housing and carrying a lysis buffer configured to lyse cells of the biological sample;
a cap configured to cooperatively couple to the housing;
a compressor configured to compress the lysis buffer storage chamber and expel the lysis buffer from the lysis buffer storage chamber and into the lysis chamber when the cap is uncoupled from the housing; and
a porous membrane in selective fluidic communication with the lysis chamber.