US 12,383,559 B2
Rehydration composition and method of use
Baruch Halpern, Bal Harbour, FL (US); and Joseph Marcantel, Carencro, LA (US)
Assigned to YourLifeRx, Inc., Wyckoff, NJ (US)
Filed by YourLifeRx, Inc., Wyckoff, NJ (US)
Filed on Mar. 9, 2023, as Appl. No. 18/119,776.
Prior Publication US 2024/0299397 A1, Sep. 12, 2024
Int. Cl. A61K 31/522 (2006.01); A23L 33/10 (2016.01); A61K 9/00 (2006.01); A61K 31/135 (2006.01); A61K 31/4985 (2006.01); A61K 45/06 (2006.01)
CPC A61K 31/522 (2013.01) [A23L 33/10 (2016.08); A61K 9/0095 (2013.01); A61K 31/135 (2013.01); A61K 45/06 (2013.01); A61K 31/4985 (2013.01)] 8 Claims
 
1. A rehydration and drug delivery composition consisting of:
a) one or more electrolytes;
b) one or more carbohydrates selected from the group consisting of fructose, glucose, sucralose, sucrose, leucrose, trehalose, galactose, isomaltulose, dextrose, and maltodextrin;
c) an effective amount of at least one active pharmaceutical ingredient selected from the group consisting of sildenafil, vardenafil, tadalafil, and ketamine;
d) one or more dietary or nutritional supplements selected from the group consisting of an amino acid, peptide, L-Arginine, L-Citrulline, protein, intestinal bacteria, beta-carotene, biotin, inositol, melatonin, selenium, coenzyme Q10, vitamin A, vitamin C, vitamin B6, vitamin B12, vitamin E, vitamin K, beetroot extract, garlic extract, red spinach, quercetin, pycnogenol, maca root extract, calcium, copper, DHEA, iron, sodium, phosphorous, potassium, magnesium, and zinc, or a salt thereof as electrolytes; and
e) one or more excipients;
wherein the one or more electrolytes, the one or more carbohydrates, the at least one active pharmaceutical ingredient, the one or more dietary or nutritional supplement, and the one or more excipients are provided as a mixture, in powder form;
wherein the composition provides an osmolality of about 25 mOsm/kg to about 275 mOsm/kg when solubilized in an aqueous liquid and is suitable for concurrently rehydrating and systemically delivering the active ingredient to a patient.