US 12,383,513 B1
Medicinal composition, method of manufacture, and method for treating skin ailments such as palmar-plantar erythrodysesthesia
Laura Allio, Copley, OH (US); and Michael Allio, Copley, OH (US)
Assigned to St. James Therapeutics Inc., Akron, OH (US)
Filed by St. James Therapeutics Inc., Akron, OH (US)
Filed on Sep. 16, 2022, as Appl. No. 17/932,690.
Application 17/932,690 is a division of application No. 16/523,444, filed on Jul. 26, 2019, granted, now 11,471,427.
Claims priority of provisional application 62/711,149, filed on Jul. 27, 2018.
Int. Cl. A61K 31/122 (2006.01); A61K 9/00 (2006.01); A61K 31/704 (2006.01); A61K 36/32 (2006.01); A61K 36/53 (2006.01); A61K 36/61 (2006.01); A61K 36/886 (2006.01); A61K 36/889 (2006.01); A61K 45/06 (2006.01)
CPC A61K 31/122 (2013.01) [A61K 9/0019 (2013.01); A61K 31/704 (2013.01); A61K 36/32 (2013.01); A61K 36/53 (2013.01); A61K 36/61 (2013.01); A61K 36/886 (2013.01); A61K 36/889 (2013.01); A61K 45/06 (2013.01)] 11 Claims
 
1. A method of making a topical treatment medicinal composition comprising:
providing 2-hydroxy-1,4, naphthoquinone;
combining 2-hydroxy-1,4, naphthoquinone with a glycoside to activate analgesic properties within the 2-hydroxy-1,4, naphthoquinone and form a concentrated suspension.