US 12,378,337 B2
Lipid nanodiscs solubilized through poly(acrylic acid-co-styrene) copolymers
Eric A. Appel, Palo Alto, CA (US); Anton Smith, San Francisco, CA (US); Henriette E. Autzen, San Francisco, CA (US); and Yifan Cheng, San Francisco, CA (US)
Assigned to The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US); and AARHUS UNIVERSITY, Aarhus C (DK)
Appl. No. 17/618,788
Filed by The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, Oakland, CA (US); and AARHUS UNIVERSITY, Aarhus C (DK)
PCT Filed Jun. 19, 2020, PCT No. PCT/US2020/038714
§ 371(c)(1), (2) Date Dec. 13, 2021,
PCT Pub. No. WO2020/257637, PCT Pub. Date Dec. 24, 2020.
Claims priority of provisional application 62/864,696, filed on Jun. 21, 2019.
Prior Publication US 2022/0251261 A1, Aug. 11, 2022
Int. Cl. C08F 212/08 (2006.01)
CPC C08F 212/08 (2013.01) [C08F 2438/03 (2013.01)] 21 Claims
OG exemplary drawing
 
1. A composition comprising:
a lipid; and
a copolymer, wherein the copolymer comprises monomer units of styrene, and monomer units selected from acrylic acid, and an acrylic acid derivative;
wherein the lipid and copolymer are in the form of a nanodisc assembly.