US 12,378,252 B2
Pyrrolopyrazole derivatives, preparation method thereof and application thereof in medicine
Feng Ren, Shanghai (CN); Yongmei Xu, Shanghai (CN); Xianlian Wang, Shanghai (CN); Chunlin Chen, Shanghai (CN); and Jinna Cai, Shanghai (CN)
Assigned to SHANGHAI MEDICILON INC., Shanghai (CN); and MEDICILON PRECLINICAL RESEARCH (SHANGHAI) LLC., Shanghai (CN)
Appl. No. 17/630,124
Filed by SHANGHAI MEDICILON INC., Shanghai (CN); and MEDICILON PRECLINICAL RESEARCH (SHANGHAI) LLC., Shanghai (CN)
PCT Filed Aug. 26, 2019, PCT No. PCT/CN2019/102524
§ 371(c)(1), (2) Date Jan. 25, 2022,
PCT Pub. No. WO2021/017066, PCT Pub. Date Feb. 4, 2021.
Claims priority of application No. 201910683537.5 (CN), filed on Jul. 26, 2019.
Prior Publication US 2022/0267336 A1, Aug. 25, 2022
Int. Cl. C07D 487/04 (2006.01)
CPC C07D 487/04 (2013.01) 3 Claims
 
1. A compound represented by general formula (I) or a pharmaceutically acceptable salt thereof,

OG Complex Work Unit Chemistry
wherein:
X is O;
R1 and R2 are each independently selected from hydrogen atom or fluorine atom;
R3 is hydrogen atom;
R4 is selected from C1-4 alkyl amide.