| CPC C07D 311/94 (2013.01) [B01J 25/02 (2013.01)] | 2 Claims |
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1. A method, comprising the steps of:
providing trans-cis nepetalactone;
providing sodium bicarbonate;
providing water;
providing methanol;
mixing the trans-cis nepetalactone, the sodium bicarbonate, the water, the methanol as a reaction mixture for approximately 15 hours at ambient temperature and pressure;
converting at least 95.2% of the nepetalactone to a ring open ester and/or aldehyde;
removing unreacted sodium bicarbonate via filtration;
transferring the filtered reaction mixture to a hydrogenation apparatus;
charging the hydrogenation apparatus with Raney nickel and/or Urushibara nickel; and
hydrogenating the ring open ester and/or aldehyde to generate at least one of DHN1, DHN2, and DHN3.
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