US 12,377,601 B2
Fast-eluting three-dimensionally molded object, filament for fast-eluting three-dimensionally molded object, and material for fast-eluting three-dimensionally molded object
Sorato Ikeda, Tokyo (JP); Shota Hattori, Tokyo (JP); and Masanori Kobayashi, Tokyo (JP)
Filed by ASTELLAS PHARMA INC., Tokyo (JP)
Filed on Feb. 23, 2023, as Appl. No. 18/113,482.
Application 18/113,482 is a continuation of application No. 16/088,041, abandoned, previously published as PCT/JP2017/014205, filed on Apr. 5, 2017.
Claims priority of application No. 2016-076810 (JP), filed on Apr. 6, 2016.
Prior Publication US 2023/0202096 A1, Jun. 29, 2023
Int. Cl. B29C 64/118 (2017.01); A61K 9/20 (2006.01); A61K 31/506 (2006.01); A61K 47/10 (2017.01); A61K 47/26 (2006.01); A61K 47/32 (2006.01); A61K 47/34 (2017.01); B33Y 70/00 (2020.01); C08K 5/1545 (2006.01); C08L 29/04 (2006.01); C08L 33/14 (2006.01); C08L 39/06 (2006.01); B29K 29/00 (2006.01); B29K 33/04 (2006.01); B33Y 10/00 (2015.01); B33Y 80/00 (2015.01)
CPC B29C 64/118 (2017.08) [A61K 9/20 (2013.01); A61K 31/506 (2013.01); A61K 47/10 (2013.01); A61K 47/26 (2013.01); A61K 47/32 (2013.01); A61K 47/34 (2013.01); B33Y 70/00 (2014.12); C08K 5/1545 (2013.01); C08L 29/04 (2013.01); C08L 33/14 (2013.01); C08L 39/06 (2013.01); A61K 9/2018 (2013.01); A61K 9/2027 (2013.01); A61K 9/2095 (2013.01); B29K 2029/04 (2013.01); B29K 2033/04 (2013.01); B29K 2039/06 (2013.01); B33Y 10/00 (2014.12); B33Y 80/00 (2014.12)] 13 Claims
OG exemplary drawing
 
1. A method for making a fast-eluting three-dimensionally (3-D) molded object by fused deposition modeling, the method comprising:
admixing an active component with a water-soluble thermoplastic polymer, a water-soluble sugar and/or a water-soluble sugar alcohol, and a plasticizer component to form a material for a 3-D molded object, wherein the water-soluble sugar and/or the water-soluble sugar alcohol is selected from a group consisting of maltitol, xylitol, mannitol, erythritol, sorbitol, and lactitol;
compressing and melt-kneading the material for a 3-D molded object in an extruder to form an extruded material;
subjecting the extruded material to injection molding to produce a filament; and
extruding the filament and molding a fast-eluting 3-D molded object by lamination on a 3-D molding stage by fused deposition modeling (FDM).