US 12,377,415 B2
Photoactivated selective release (PHASR) of droplets from microwell arrays
Yongwon Choi, Bryn Mawr, PA (US); Daeyeon Lee, Wynnewood, PA (US); Junhyong Kim, Narberth, PA (US); and Syung Hun Han, Austin, TX (US)
Assigned to The Trustees of the University of Pennsylvania, Philadelphia, PA (US)
Filed by The Trustees of the University of Pennsylvania, Philadelphia, PA (US)
Filed on Dec. 27, 2021, as Appl. No. 17/562,250.
Claims priority of provisional application 63/132,270, filed on Dec. 30, 2020.
Prior Publication US 2022/0203370 A1, Jun. 30, 2022
Int. Cl. B01L 3/00 (2006.01); B81B 1/00 (2006.01); G01N 15/01 (2024.01); G01N 15/1434 (2024.01)
CPC B01L 3/502784 (2013.01) [B81B 1/006 (2013.01); G01N 15/1434 (2013.01); B01L 2200/027 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/1872 (2013.01); B01L 2400/0442 (2013.01); B81B 2201/057 (2013.01); B81B 2203/033 (2013.01); B81B 2203/0338 (2013.01); G01N 15/01 (2024.01)] 19 Claims
OG exemplary drawing
 
1. A microfluidic device comprising:
a well substrate having a plurality of wells defined in the well substrate, each well of the plurality of wells having a first opening and a second opening;
a photoresponsive layer sealing the first opening of each well of the plurality of wells; and
a trap channel in fluidic communication with the second opening of each well of the plurality of wells.