US 12,377,201 B2
Flow cell
Jon A. Dodd, Littleton, CO (US); Daniel Clement, Lakewood, CO (US); Dennis J. Hlavinka, Arvada, CO (US); Jeremy T. Parsons, Denver, CO (US); and Haralambos P. Apostolopoulos, Castle Rock, CO (US)
Assigned to Terumo BCT Biotechnologies, LLC, Lakewood, CO (US)
Filed by Terumo BCT Biotechnologies, LLC, Lakewood, CO (US)
Filed on Aug. 30, 2023, as Appl. No. 18/458,544.
Application 18/458,544 is a division of application No. 16/523,976, filed on Jul. 26, 2019, granted, now 11,771,814.
Claims priority of provisional application 62/829,815, filed on Apr. 5, 2019.
Claims priority of provisional application 62/711,283, filed on Jul. 27, 2018.
Prior Publication US 2023/0405204 A1, Dec. 21, 2023
Int. Cl. A61M 1/36 (2006.01); A61K 41/10 (2020.01); A61L 2/00 (2006.01); A61M 1/34 (2006.01); B01L 3/00 (2006.01)
CPC A61M 1/3681 (2013.01) [A61L 2/0011 (2013.01); A61M 1/3455 (2013.01); A61M 1/3683 (2014.02); A61M 1/3689 (2014.02); B01L 3/502 (2013.01); A61K 41/10 (2020.01); A61M 2206/10 (2013.01); B01L 2300/0877 (2013.01); B01L 2300/0883 (2013.01); B01L 2300/12 (2013.01); B01L 2300/123 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A flow cell for manipulating a fluid, the flow cell comprising
an inlet;
a first channel extending from the first inlet in a first plane;
a first splitter in fluid communication with the first channel, the first splitter extending from the first plane to a second plane that is parallel to the first plane, the first splitter extending perpendicular to the first plane and the second plane;
a second channel in fluid communication with the first splitter and a first elbow, the second channel extending in the first plane;
a third channel in fluid communication with the first splitter and a second elbow, the third channel extending in the second plane;
a third elbow in the first plane and in fluid communication with the first elbow;
a first recombiner in fluid communication with the third elbow and the second elbow, the first recombiner extending perpendicular to the first plane and the second plane;
a fourth channel in fluid communication with the first recombiner, the fourth channel extending in the second plane;
a second splitter in the second plane and in fluid communication with the fourth channel;
a fifth channel in the second plane and in fluid communication with the second splitter and a fifth elbow configured to direct the fluid from the second plane to the first plane;
a sixth channel in the second plane and in fluid communication with the second splitter and a sixth elbow configured to direct the fluid from the second plane to the first plane;
a second recombiner in the first plane and in fluid communication with a seventh elbow opposite to the fifth elbow and an eighth elbow opposite to the sixth elbow;
a seventh channel in fluid communication with the second recombiner, wherein at least one of the first channel, the second channel, the third channel, the fourth channel, the fifth channel, the sixth channel, or the seventh channel comprises a first dimension that is between about 0.5 mm and about 5 mm; and
an outlet, the seventh channel extending to the outlet,
wherein the first channel, the second channel, the third channel, the fourth channel, the fifth channel, the sixth channel, and the seventh channel are together configured to direct the fluid through all three dimensions of a three-dimensional space.