	US 12,377,190 B2
	Acoustically responsive biomaterials
Rosalyn Abbott-Beauregard, Pittsburgh, PA (US); and Megan Debari, Pittsburgh, PA (US)
Assigned to CARNEGIE MELLON UNIVERSITY, Pittsburgh, PA (US)
Appl. No. 18/554,058
Filed by CARNEGIE MELLON UNIVERSITY, Pittsburgh, PA (US)
PCT Filed Apr. 26, 2022, PCT No. PCT/US2022/026271 § 371(c)(1), (2) Date Oct. 5, 2023, PCT Pub. No. WO2022/232090, PCT Pub. Date Nov. 3, 2022.
Claims priority of provisional application 63/181,601, filed on Apr. 29, 2021.
Prior Publication US 2024/0366835 A1, Nov. 7, 2024
Int. Cl. A61K 36/00 (2006.01); A61L 27/22 (2006.01); A61L 27/36 (2006.01); D01F 4/02 (2006.01)

CPC A61L 27/227 (2013.01) [A61L 27/3604 (2013.01); A61L 27/3687 (2013.01); D01F 4/02 (2013.01)]

10 Claims

1. A method for creating a silk fibroin tissue scaffold comprising:

preparing a silk solution comprising silk fibroin extracted from silk cocoons;

adding a volume of gas vesicles to the silk solution; and

solidifying the silk solution;

wherein the gas vesicles are derived from bacteria.