| CPC A61B 34/10 (2016.02) [A61B 34/30 (2016.02); A61F 2/44 (2013.01); G06N 20/00 (2019.01); G06T 7/0012 (2013.01); G16H 50/20 (2018.01); G16H 50/30 (2018.01); G16H 50/50 (2018.01); A61B 2034/102 (2016.02); A61B 2034/105 (2016.02); A61B 2034/108 (2016.02); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30012 (2013.01)] | 28 Claims |

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1. A computer-implemented method, comprising:
performing a digital surgical simulation for each of a plurality of candidate patient-specific surgical interventions that each provide a corresponding patient-specific anatomical correction, the digital surgical simulations each including a corresponding predictive model of patient anatomy for a particular time after the corresponding candidate patient-specific interventions, wherein the digital surgical simulations are performed at least in part by at least one trained machine learning module trained using reference patient data;
displaying surgical simulation data from at least one of the digital surgical simulations, wherein the surgical simulation data includes the corresponding predictive model of patient anatomy for user review;
receiving a selection of one of the plurality of candidate patient-specific surgical interventions; and
designing one or more patient-specific implants based on the selected candidate patient-specific surgical intervention, wherein the one or more patient-specific implants are configured to achieve a patient-specific anatomical correction associated with the selected candidate patient-specific surgical intervention when implanted in a patient with the patient anatomy.
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