US 12,376,754 B2
Biomarker monitoring sensor and methods of use
Moussa Bteich, Faraya (LB); Joseph Costantine, Albuquerque, NM (US); Rouwaida Kanj, Portland, OR (US); Assaad Eid, Paris (FR); Youssef Tawk, Albuquerque, NM (US); and Ali H. Ramadan, Beirut (LB)
Assigned to American University of Beirut, Beirut (LB)
Filed by American University of Beirut, Beirut (LB)
Filed on Aug. 23, 2021, as Appl. No. 17/409,177.
Application 17/409,177 is a continuation of application No. PCT/US2020/020388, filed on Feb. 28, 2020.
Claims priority of provisional application 62/811,760, filed on Feb. 28, 2019.
Prior Publication US 2022/0039682 A1, Feb. 10, 2022
Int. Cl. A61B 5/0507 (2021.01); A61B 5/00 (2006.01); A61B 5/145 (2006.01)
CPC A61B 5/0507 (2013.01) [A61B 5/14532 (2013.01); A61B 5/14546 (2013.01); A61B 5/6806 (2013.01); A61B 5/681 (2013.01); A61B 2562/0228 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A sensor to non-invasively detect a concentration of biomarkers comprising: a miniaturized electromagnetic based passive microwave circuitry to extract an electrical property of a body constituent the miniaturized electromagnetic based passive microwave circuitry targeting at least one of radial, median, cephalic, or ulnar arteries comprising, a sensing device to be placed near the body; an RF energy source; an RF energy converter to convert RF energy into phase and magnitude parameters; a phase and magnitude converter to provide concentration information of the body constituent; wherein the microwave circuitry covers a microwave spectrum and the microwave circuitry reacts to loading by the body constituent; wherein the microwave circuitry is reconfigurable to allow frequency tuning, the microwave circuitry includes a plurality of open loop resonators ranging between 1.5 GHZ and 2.5 GHz to operate as a multiband and reconfigurable filter; the microwave circuitry attains a high sensitivity to lossy material over a 1.25 and 2.25 GHz frequency span; eight stop bands ranging between 1.5 GHz and 2.5 GHz and the eight stop bands are separated by seven pass bands.