US 12,371,569 B2
Low endotoxin gelatin-(meth)acryloyl
Bjorn Vergauwen, Ghent (BE); and Elke De Clerck, Ghent (BE)
Assigned to ROUSSELOT BV, Ghent (BE)
Appl. No. 17/917,774
Filed by ROUSSELOT BV, Ghent (BE)
PCT Filed May 19, 2021, PCT No. PCT/EP2021/063257
§ 371(c)(1), (2) Date Oct. 7, 2022,
PCT Pub. No. WO2021/233981, PCT Pub. Date Nov. 25, 2021.
Claims priority of application No. 2020/5347 (BE), filed on May 19, 2020.
Prior Publication US 2023/0133041 A1, May 4, 2023
Int. Cl. C08L 89/06 (2006.01); A61L 27/22 (2006.01); A61L 27/52 (2006.01); C08J 3/075 (2006.01)
CPC C08L 89/06 (2013.01) [A61L 27/222 (2013.01); A61L 27/52 (2013.01); C08J 3/075 (2013.01); C08J 2389/06 (2013.01); C08L 2203/16 (2013.01)] 10 Claims
 
1. A gelatin modified with a methacryloyl group or an acryloyl group, having a lipopolysaccharide content of less than 100 EU/g, less than 50 EU/g, less than 20 EU/g, less than 10 EU/g, less than 5 EU/g, less than 2 EU/g, or less than 1 EU/g, and
comprising less than 30 ppm of a methacrylic acid or an acrylic acid,
wherein the methacrylic acid or the acrylic acid content is determined on a sample of the gelatin dissolved in water, or
comprising less than 100 ppm of a methacrylic acid or an acrylic acid,
wherein the methacrylic acid or acrylic acid content is determined on a sample of the gelatin dissolved in 50 mM phosphate buffer, pH 9.5.