US 12,360,047 B2
Characteristic information extraction method and portable detection system for small-molecule volatile substances
Quansheng Chen, Zhenjiang (CN); Huanhuan Li, Zhenjiang (CN); Qin Ouyang, Zhenjiang (CN); Jiaji Zhu, Zhenjiang (CN); Yi Xu, Zhenjiang (CN); Tianhui Jiao, Zhenjiang (CN); and Haihui Pan, Zhenjiang (CN)
Assigned to JIANGSU UNIVERSITY, Zhenjiang (CN)
Filed by JIANGSU UNIVERSITY, Zhenjiang (CN)
Filed on Apr. 28, 2023, as Appl. No. 18/309,578.
Application 18/309,578 is a continuation of application No. PCT/CN2021/104632, filed on Jul. 6, 2021.
Prior Publication US 2023/0266249 A1, Aug. 24, 2023
Int. Cl. G01N 21/65 (2006.01); G01N 21/01 (2006.01); G01N 21/03 (2006.01); G06N 3/045 (2023.01); G06N 3/08 (2023.01)
CPC G01N 21/658 (2013.01) [G01N 21/03 (2013.01); G06N 3/045 (2023.01); G06N 3/08 (2013.01); G01N 2021/0131 (2013.01); G01N 2021/0325 (2013.01); G01N 2201/06113 (2013.01); G01N 2201/0638 (2013.01); G01N 2201/0683 (2013.01); G01N 2201/0697 (2013.01); G01N 2201/129 (2013.01)] 11 Claims
OG exemplary drawing
 
1. A detection system for a small-molecule volatile substance, comprising:
a surface-enhanced Raman scattering (SERS) response medium;
a reaction device;
a Raman spectrum detection device; and
a server;
wherein the SERS response medium is configured to enhance a Raman scattering intensity of the small-molecule volatile substance;
the reaction device is configured to allow the small-molecule volatile substance and the SERS response medium to react thereon;
the Raman spectrum detection device is configured to collect a SERS spectrum of the small-molecule volatile substance after a reaction between the small-molecule volatile substance and the SERS response medium, and send the SERS spectrum to the server;
wherein the Raman spectrum detection device comprises:
a light source module;
a light path module;
a signal processing module; and
a control module;
the control module is in wire connection with the light source module, the light path module and the signal processing module;
the light source module comprises a semiconductor laser and a pulsed laser device; and the pulsed laser device is configured to generate a pulse laser and transmit the pulse laser to the light path module;
the light path module comprises an attenuation assembly, a beam expansion-shaping assembly and a collection assembly;
the signal processing module comprises a spectrometer and a detector;
the control module comprises a time-sequence controller; the time-sequence controller is connected to the pulsed laser device and the detector, and is configured to adjust the pulsed laser device and the detector, so as to realize synchronization between a pulse time sequence of the pulsed laser device and a shutter time sequence of the detector;
the server is signally connected to the Raman spectrum detection device; and the server is configured to perform a detection method for the small-molecule volatile substance through steps of:
(1) generating the pulse laser, by the pulsed laser device, to form a first laser beam, and focusing the first laser beam on the small-molecule volatile substance;
(2) receiving and processing a second laser beam scattered by the small-molecule volatile substance to obtain the SERS spectrum of the small-molecule volatile substance;
(3) dividing the SERS spectrum of the small-molecule volatile substance to obtain n wavelength subintervals, wherein n is a positive integer;
(4) sampling the n wavelength subintervals through weighted bootstrap sampling (WBS) to obtain W wavelength subintervals, wherein W is a positive integer less than n;
(5) screening the W wavelength subintervals to obtain a desired wavelength subset; and
(6) inputting the desired wavelength subset into an estimation model to construct a mathematical relationship between content of the small-molecule volatile substance and the desired wavelength subset.