US 12,359,190 B2
Systems, devices, and methods for isotachophoresis
Lewis A. Marshall, Oakland, CA (US); Amy L Hiddessen, Pleasanton, CA (US); Nathan P. Hoverter, Pleasanton, CA (US); Klint A. Rose, Oakland, CA (US); Juan G. Santiago, Stanford, CA (US); Matthew S. Munson, Evanston, IL (US); Janine Mok, Palo Alto, CA (US); Sean Arin, Oakland, CA (US); Yatian Qu, Sunnyvale, CA (US); Andrew Lee, Hayward, CA (US); and Michael Christopher De Renzi, Pleasanton, CA (US)
Assigned to Purigen Biosystems, Inc., Pleasanton, CA (US)
Filed by Purigen Biosystems, Inc., Pleasanton, CA (US)
Filed on Aug. 8, 2023, as Appl. No. 18/231,601.
Application 17/230,582 is a division of application No. 16/052,565, filed on Aug. 1, 2018, granted, now 11,041,150, issued on Jun. 22, 2021.
Application 18/231,601 is a continuation of application No. 17/230,582, filed on Apr. 14, 2021, granted, now 11,987,789.
Claims priority of provisional application 62/540,515, filed on Aug. 2, 2017.
Claims priority of provisional application 62/541,086, filed on Aug. 3, 2017.
Claims priority of provisional application 62/541,089, filed on Aug. 3, 2017.
Prior Publication US 2023/0383280 A1, Nov. 30, 2023
Int. Cl. C12N 15/10 (2006.01); B01L 3/00 (2006.01); B01L 9/00 (2006.01); G01N 27/447 (2006.01)
CPC C12N 15/101 (2013.01) [B01L 3/502738 (2013.01); B01L 3/502746 (2013.01); B01L 3/502761 (2013.01); B01L 3/502776 (2013.01); B01L 3/5085 (2013.01); G01N 27/44717 (2013.01); B01L 9/527 (2013.01); B01L 2200/0621 (2013.01); B01L 2200/0642 (2013.01); B01L 2400/0421 (2013.01); B01L 2400/0688 (2013.01); G01N 27/44704 (2013.01); G01N 27/44743 (2013.01); G01N 27/44791 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A fluidic device comprising an isotachophoresis (ITP) circuit comprising:
a first channel comprising first and second capillary barriers that are spaced apart; and
a first loading reservoir in fluid communication with said first channel via a first aperture in said first channel, wherein said first aperture is positioned between said first and second capillary barriers to permit a first liquid entering said first channel via said first aperture to flow in one direction along said first channel and arrest at said first capillary barrier and to flow in another direction along said first channel and arrest at said second capillary barrier,
wherein said first liquid entering said first channel via said first aperture flows along a path to said first capillary barrier that is longer than a width of said first channel, and said first liquid entering said first channel via said first aperture flows along a path to said second capillary barrier that is longer than the width of said first channel.