	US 12,358,882 B2
	Carbonate-promoted carboxylation at high rates
Matthew W. Kanan, Palo Alto, CA (US); Aanindeeta Banerjee, Oakland, CA (US); and Amy Delano Frankhouser, Oakland, CA (US)
Assigned to The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US)
Appl. No. 17/793,890
Filed by The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US)
PCT Filed Feb. 5, 2021, PCT No. PCT/US2021/016772 § 371(c)(1), (2) Date Jul. 19, 2022, PCT Pub. No. WO2021/158890, PCT Pub. Date Aug. 12, 2021.
Claims priority of provisional application 62/970,969, filed on Feb. 6, 2020.
Prior Publication US 2023/0048043 A1, Feb. 16, 2023
Int. Cl. C07D 307/68 (2006.01)

CPC C07D 307/68 (2013.01)

20 Claims

1. A method for synthesizing furan-2, 5-dicarboxylate (FDCA²⁻⁾, comprising:

providing furan-2-carboxylate;

providing an inorganic base in a form of an inorganic base salt, wherein the furan-2-carboxylate and the inorganic base salt form a mixture;

providing a CO₂gas to the mixture;

heating the mixture to a temperature to at least partially melt the mixture, wherein the heating of the mixture causes the synthesizing of a M_xFDCA solid, wherein M_xFDCA denotes a salt comprising furan-2,5-dicarboxylate (FDCA²⁻⁾and cation M⁺ or M²⁺, where x is a number between 1 and 2, inclusive; and

mechanically agitating the mixture containing furan-2-carboxylate, wherein the mechanically agitating breaks up the M_xFDCA solid.