US 12,357,776 B2
Medicinal inhalers
David J. Cottenden, Melbourn (GB); Christopher G. Blatchford, Loughborough (GB); William T. Richardson, Royston (GB); Romain U. G. Guion, Cambridge (GB); Iain G. McDerment, Melbourn (GB); Christopher B. J. Groombridge, Stevenage (GB); and Simon L. Calcutt, Cambridge (GB)
Assigned to Kindeva Drug Delivery L.P., St. Paul, MN (US)
Appl. No. 16/064,433
Filed by KINDEVA DRUG DELIVERY L.P., St. Paul, MN (US)
PCT Filed Dec. 6, 2016, PCT No. PCT/US2016/065113
§ 371(c)(1), (2) Date Jun. 20, 2018,
PCT Pub. No. WO2017/112400, PCT Pub. Date Jun. 29, 2017.
Claims priority of provisional application 62/270,081, filed on Dec. 21, 2015.
Claims priority of provisional application 62/289,676, filed on Feb. 1, 2016.
Prior Publication US 2019/0001085 A1, Jan. 3, 2019
Int. Cl. A61H 15/00 (2006.01); A61M 15/00 (2006.01); A61M 16/00 (2006.01)
CPC A61M 15/0091 (2013.01) [A61M 15/002 (2014.02); A61M 15/009 (2013.01); A61M 2016/0018 (2013.01); A61M 2016/0027 (2013.01); A61M 2205/0266 (2013.01); A61M 2205/3331 (2013.01); A61M 2205/3334 (2013.01); A61M 2205/3341 (2013.01); A61M 2205/3358 (2013.01); A61M 2205/50 (2013.01); A61M 2205/8206 (2013.01); A61M 2205/8281 (2013.01)] 13 Claims
OG exemplary drawing
 
1. A medicinal inhaler comprising:
a housing;
an air flow path defined by at least partially the housing and including an air inlet and an air outlet;
a flow governor positioned in the air flow path between the air inlet and the air outlet to govern air flow in the air flow path to a governing volumetric flow rate;
a breath-actuated dose release firing system located in the housing, wherein the firing system is configured to release a dose of medicament at a firing volumetric flow rate less than the governing volumetric flow rate; and
an inspiratory air flow detection system configured to detect an inspiratory air flow rate in the air flow path and to send an electrical signal to the firing system to fire when the inspiratory air flow rate is equal to at least the firing volumetric flow rate, wherein the inspiratory air flow detection system comprises a pressure sensor located in the air flow path upstream of the flow governor and downstream of the air inlet, and wherein the inspiratory air flow detection system further comprises a controller connected to the pressure sensor and the breath-actuated dose release firing system.