US 12,357,763 B2
Injection device
Michael Dahmen, Kronberg (DE); and Hannes Obex, Dusseldorf (DE)
Assigned to Sanofi-Aventis Deutschland GMBH, Frankfurt am Main (DE)
Appl. No. 17/269,646
Filed by Sanofi-Aventis Deutschland GMBH, Frankfurt am Main (DE)
PCT Filed Aug. 27, 2019, PCT No. PCT/EP2019/072759
§ 371(c)(1), (2) Date Feb. 19, 2021,
PCT Pub. No. WO2020/043685, PCT Pub. Date Mar. 5, 2020.
Claims priority of application No. 18191424 (EP), filed on Aug. 29, 2018.
Prior Publication US 2021/0361876 A1, Nov. 25, 2021
Int. Cl. A61M 5/315 (2006.01); A61M 5/24 (2006.01)
CPC A61M 5/31543 (2013.01) [A61M 5/24 (2013.01); A61M 5/31501 (2013.01); A61M 5/31551 (2013.01); A61M 2005/2477 (2013.01); A61M 2005/2485 (2013.01); A61M 2005/3154 (2013.01)] 27 Claims
OG exemplary drawing
 
1. An injection device, comprising
a housing having a central axis,
a cartridge holder for receiving a cartridge containing a medicament, the cartridge holder having a first attachment member,
a threaded sleeve insert axially and rotationally constrained to the housing, the threaded sleeve insert having a second attachment member, and
a metering mechanism, the metering mechanism comprising
an actuating element for setting or discharging a dose of the medicament from the injection device,
a piston rod for producing an advance movement for dispensing a dose,
a piston rod sleeve for accommodating the piston rod, wherein the piston rod is non-rotatably connected to the piston rod sleeve, and
a coupling element for coupling the actuating element and the piston rod sleeve to discharge the dose with the actuating element in a manner such that a dispensing movement of the actuating element is transmitted to the piston rod by the piston rod sleeve,
wherein the metering mechanism further comprises a reverse rotation prevention element for the piston rod sleeve, to permit rotation of the piston rod sleeve in one direction and to prevent rotation of the piston rod sleeve in an opposite direction,
wherein the piston rod is non-rotatably connected to the piston rod sleeve by a coupling sleeve, wherein the coupling sleeve engages the piston rod sleeve to form a non-rotatable connection between the piston rod and the coupling sleeve, and wherein the piston rod is rotatable relative to the piston rod sleeve when the coupling sleeve is out of engagement with the piston rod sleeve,
wherein the cartridge holder is configured to move axially with respect to the threaded sleeve insert and the housing to attach the cartridge holder to the threaded sleeve insert by an interaction of the first attachment member and the second attachment member and wherein the cartridge holder is configured to bring the coupling sleeve into engagement with the piston rod sleeve by means of said axial movement with respect to the threaded sleeve insert and the housing.