| CPC A61L 15/425 (2013.01) [A61L 15/225 (2013.01); A61L 15/28 (2013.01); A61L 15/325 (2013.01); A61L 15/58 (2013.01); A61L 2300/608 (2013.01); A61L 2400/04 (2013.01)] | 25 Claims |

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1. A medical device comprising:
a. a first porous substrate layer having at least one major facing surface with at least a surface coating thereon of a first co-reactive component in a dry form;
b. a second substrate layer having at least one major facing surface with at least a surface coating layer of a second co-reactive component in a dry form that reacts with the first co-reactive component; and
c. a removable inert barrier film layer positioned between the first porous substrate layer and second substrate layer and in contact with at least one major facing surface or a surface coating, each, independently of one another, from said first porous substrate layer and said second substrate layer,
wherein said inert barrier film layer is removable from between the first porous substrate layer and the second substrate layer by pulling, and wherein at least one peripheral edge of the barrier layer extends beyond a peripheral edge of at least one of the first porous substrate layer and the second substrate layer.
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