US 12,357,710 B2
Radiopaque contrast agent
Michael Scott Echols, Salt Lake City, UT (US)
Assigned to SICREATIONS, LLC, Salt Lake City, UT (US)
Filed by Scarlet Imaging, LLC, Salt Lake City, UT (US)
Filed on Aug. 26, 2015, as Appl. No. 14/836,717.
Application 14/836,717 is a continuation in part of application No. 14/446,111, filed on Jul. 29, 2014, abandoned.
Prior Publication US 2016/0030601 A1, Feb. 4, 2016
Int. Cl. A61K 49/04 (2006.01)
CPC A61K 49/0404 (2013.01) [A61K 49/0419 (2013.01)] 18 Claims
 
1. A process of preparing for imaging a vascular system of a subject having capillaries comprising:
placing a live subject under anesthesia or sedation;
placing and securing a first intravenous (IV) catheter and a second IV catheter at opposite ends of a vessel in the body of said subject;
ligating or occluding a section of said vessel between said first IV catheter and said second IV catheter;
flushing isotonic fluid through the vascular system in an amount to 20-60 total weight percent of a body of the subject to produce clear to weak blood tinged fluid exiting said second IV catheter;
infusing a radiopaque composition comprising: an opacifying agent having a size of less than 10 microns; an aqueous gelatinous substance present from 5 to 20 percent weight by volume into said first IV catheter at a temperature of 45 to 90 degrees Celsius until said subject is fully perfused with said radiopaque composition; and
waiting a time interval for said radiopaque composition to cool and form a solid gel to uniformly fill the capillaries as part of fill of the complete vascular system.