US 12,357,581 B2
Nanoparticles comprising copolymeric or homopolymeric compounds which comprise cyanoacrylate subunits
Ruth Schmid, Tiller (NO); Peter Molesworth, Leirfossvegen (NO); and Yrr Mørch, Trondheim (NO)
Assigned to SINTEFF TTO AS, (NO)
Appl. No. 17/602,344
Filed by SINTEF TTO AS, Trondheim (NO)
PCT Filed Feb. 26, 2020, PCT No. PCT/EP2020/055066
§ 371(c)(1), (2) Date Oct. 8, 2021,
PCT Pub. No. WO2020/207655, PCT Pub. Date Oct. 15, 2020.
Claims priority of application No. 20190491 (NO), filed on Apr. 10, 2019.
Prior Publication US 2022/0160645 A1, May 26, 2022
Int. Cl. A61K 31/337 (2006.01); A61K 9/51 (2006.01)
CPC A61K 9/5138 (2013.01) [A61K 31/337 (2013.01)] 20 Claims
 
1. A nanoparticle comprising copolymeric or homopolymeric compounds which comprise cyanoacrylate subunits according to formula 2A:

OG Complex Work Unit Chemistry
wherein each R1 is independently selected from the group consisting of 2-ethylhexyl, 2-phenyl-ethyl, neopentyl, 1-pentyl, 2-pentyl, 3-pentyl, 3,3-dimethyl-1-butyl, 3-methylbutyl, 1-heptyl, 2-heptyl, and 3-heptyl;
and wherein the nanoparticle further comprises an active agent.