US 12,357,569 B2
Infusing drug solution directly into brain fluid
Daniel J. Abrams, Aurora, CO (US); and Michael S. Canney, Denver, CO (US)
Assigned to Biogen MA Inc., Cambridge, MA (US)
Filed by Biogen MA Inc., Cambridge, MA (US)
Filed on Sep. 1, 2022, as Appl. No. 17/901,360.
Application 17/901,360 is a continuation of application No. 16/252,113, filed on Jan. 18, 2019, abandoned.
Application 16/252,113 is a continuation in part of application No. 15/663,095, filed on Jul. 28, 2017, granted, now 11,511,035.
Claims priority of provisional application 62/367,713, filed on Jul. 28, 2016.
Prior Publication US 2022/0409530 A1, Dec. 29, 2022
Int. Cl. A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 45/06 (2006.01); A61M 25/00 (2006.01); A61P 25/08 (2006.01); A61M 25/01 (2006.01); A61M 39/02 (2006.01)
CPC A61K 9/0085 (2013.01) [A61K 9/08 (2013.01); A61K 45/06 (2013.01); A61M 25/0043 (2013.01); A61P 25/08 (2018.01); A61M 2025/0056 (2013.01); A61M 2025/0175 (2013.01); A61M 39/0208 (2013.01)] 12 Claims
OG exemplary drawing
 
1. An intraventricular access device comprising:
a container configured to couple to an aspiration lumen through which cerebrospinal fluid (CSF) may be aspirated or through which drugs may be injected,
wherein the container is further configured to couple to a catheter configured to couple to a drug pump,
the container is further configured to couple to an infusion lumen,
wherein the container comprises:
an infusion pathway connectable to the catheter through which a drug from the drug pump may be infused to flow through the infusion lumen into the CSF;
a portion formed from material that is penetrable by a needle and which substantially reseals upon extraction of the needle, wherein the container is configured such that penetration of the needle through the portion places the needle in fluid communication with a volume within the container that is in fluid communication with the aspiration lumen; and
a barrier configured to inhibit penetration of the needle into the infusion pathway when the needle is in fluid communication with the volume within the container that is in fluid communication with the aspiration lumen,
wherein the container includes a marker that is a distinct structure from the barrier and configured to directly indicate a position of the barrier during and/or after implantation of the container, and
wherein the container is configured to prevent cross contamination between a first fluid in the aspiration lumen and a second fluid in the infusion lumen.