	US 12,357,567 B2
	Nebulization formulations for delivery to lower respiratory tract
Jay Richard Ray, II, Conroe, TX (US)
Assigned to CMPD Licensing, LLC, Conroe, TX (US)
Filed by CMPD Licensing, LLC, Conroe, TX (US)
Filed on Nov. 27, 2023, as Appl. No. 18/519,955.
Application 18/519,955 is a continuation of application No. 17/740,790, filed on May 10, 2022, granted, now 11,826,465, issued on Nov. 28, 2023.
Application 17/740,790 is a continuation of application No. 17/513,759, filed on Oct. 28, 2021, granted, now 11,324,694, issued on May 10, 2022.
Prior Publication US 2024/0082152 A1, Mar. 14, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. A61K 9/00 (2006.01); A61J 3/07 (2006.01); A61K 31/135 (2006.01); A61K 31/197 (2006.01); A61K 31/439 (2006.01); A61K 31/522 (2006.01); A61K 33/30 (2006.01); A61K 45/06 (2006.01); A61K 47/12 (2006.01); A61K 47/26 (2006.01)

CPC A61K 9/0078 (2013.01) [A61J 3/078 (2013.01); A61K 31/135 (2013.01); A61K 31/197 (2013.01); A61K 31/439 (2013.01); A61K 31/522 (2013.01); A61K 33/30 (2013.01); A61K 45/06 (2013.01); A61K 47/12 (2013.01); A61K 47/26 (2013.01)]

21 Claims

1. A method of treating lower respiratory tract related non-infective conditions or symptoms, the method comprising:

administering a unit dose of a nebulizer solution or suspension to a subject via nebulization to a lower respiratory tract of the subject to treat a non-infective condition or symptom related to the lower respiratory tract, wherein the nebulizer solution or suspension comprises:

a beta agonist or an anticholinergic,

acetylcysteine in a unit dose amount of about 0.5 mg to about 100 mg, and

a diluent.