US 12,357,449 B2
Systems and methods for treating ocular disease with an intraocular lens and refractive index writing
Robert Rosen, Groningen (NL); Franck Emmanuel Gounou, Groningen (NL); Carmen Canovas Vidal, Groningen (NL); and Aixa Alarcon Heredia, Groningen (NL)
Assigned to AMO Groningen B.V., (NL)
Filed by AMO Groningen B.V., Groningen (NL)
Filed on Jun. 19, 2023, as Appl. No. 18/337,393.
Application 18/337,393 is a division of application No. 16/837,742, filed on Apr. 1, 2020, granted, now 11,678,975.
Claims priority of provisional application 62/830,261, filed on Apr. 5, 2019.
Prior Publication US 2023/0404743 A1, Dec. 21, 2023
This patent is subject to a terminal disclaimer.
Int. Cl. A61F 2/16 (2006.01); A61F 9/008 (2006.01); B29D 11/00 (2006.01); A61B 17/00 (2006.01)
CPC A61F 2/1627 (2013.01) [A61F 9/008 (2013.01); A61F 9/00834 (2013.01); B29D 11/00355 (2013.01); B29D 11/00461 (2013.01); A61B 2017/00181 (2013.01); A61F 2009/00848 (2013.01)] 18 Claims
OG exemplary drawing
 
1. A method of treating an ocular disease of a subject having an implanted intraocular lens (IOL), the method comprising:
determining visual needs of the subject that are associated with the ocular disease of the subject;
determining a pattern of a plurality of laser pulses to apply, by refractive index writing, to one or more selected areas of the IOL, wherein the determined pattern of the plurality of laser pulses is configured to induce a change in the implanted IOL to adapt the optical performance of the IOL to the visual needs of the subject; and
wherein determining the pattern of the plurality of laser pulses to apply comprises calculating a radius of a phase shift for correcting for a residual spherical error, the radius of the phase shift being calculated according to factors that include an angular dependence and, at least in part, according to:

OG Complex Work Unit Math
where λ is the wavelength, m is a natural number, θ is the angle, and F1 and F2 the power to be corrected in the respective meridians; and
applying, according to the determined pattern, the plurality of focused laser pulses to the one or more selected areas of the IOL.
 
16. A method of treating an ocular disease of a subject having an implanted intraocular lens (IOL), the method comprising:
determining visual needs of the subject that are associated with the ocular disease of the subject;
determining a pattern of a plurality of laser pulses to apply, by refractive index writing, to one or more selected areas of the IOL, wherein the determined pattern of the plurality of laser pulses is configured to induce a change in the implanted IOL to adapt the optical performance of the IOL to the visual needs of the subject;
determining parameters of a prism to be produced on the IOL to correct negative dysphotopsia of the subject, wherein the determining parameters comprises defining the prism based on power of the IOL and extension of the prism from respective outer edges of the IOL to the center of the IOL;
wherein determining the pattern of the plurality of laser pulses to apply comprises determining a pattern of a plurality of laser pulses to apply to produce, through refractive index writing on the IOL, the prism having the determined parameters; and
applying, according to the determined pattern, the plurality of focused laser pulses to the one or more selected areas of the IOL.