US 12,357,311 B2
Conductive scaffolds for guided neural network formation
Hongjun Wang, Millburn, NJ (US); Haoyu Wang, Lyndhurst, NJ (US); and Juan Wang, Shanghai (CN)
Assigned to The Trustees of the Stevens Institute of Technology, Hoboken, NJ (US)
Appl. No. 18/020,049
Filed by The Trustees of The Stevens Institute of Technology, Hoboken, NJ (US)
PCT Filed Aug. 6, 2021, PCT No. PCT/US2021/045117
§ 371(c)(1), (2) Date Feb. 6, 2023,
PCT Pub. No. WO2022/032203, PCT Pub. Date Feb. 10, 2022.
Claims priority of provisional application 63/063,158, filed on Aug. 7, 2020.
Prior Publication US 2023/0293179 A1, Sep. 21, 2023
Int. Cl. A61B 17/11 (2006.01); A61L 31/06 (2006.01); A61L 31/10 (2006.01); A61L 31/14 (2006.01); B33Y 10/00 (2015.01); B33Y 40/20 (2020.01); B33Y 70/00 (2020.01); B33Y 80/00 (2015.01); B41M 5/00 (2006.01); A61B 17/00 (2006.01); A61N 1/36 (2006.01)
CPC A61B 17/1128 (2013.01) [A61L 31/06 (2013.01); A61L 31/10 (2013.01); A61L 31/14 (2013.01); B33Y 10/00 (2014.12); B33Y 40/20 (2020.01); B33Y 70/00 (2014.12); B33Y 80/00 (2014.12); B41M 5/0047 (2013.01); A61B 2017/00526 (2013.01); A61L 2420/02 (2013.01); A61L 2430/32 (2013.01); A61N 1/36103 (2013.01)] 14 Claims
OG exemplary drawing
 
1. A method for making an electrically-conductive scaffold, comprising the steps of:
obtaining a biomimetic matrix, wherein said obtaining step comprises the step of printing said biomimetic matrix via near-field electrostatic printing;
providing said biomimetic matrix with an electrically-conductive pattern of reduced graphene oxide by applying a cationic polyelectrolyte to said biomimetic matrix and directly coating said biomimetic matrix with a graphene oxide solution to form a graphene oxide coating; and
reducing said graphene oxide coating into said pattern of reduced graphene oxide.