US 12,031,943 B2
Ion analyzer
Hidenori Takahashi, Kyoto (JP); and Daiki Asakawa, Tsukuba (JP)
Assigned to SHIMADZU CORPORATION, Kyoto (JP); and NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, Tokyo (JP)
Appl. No. 17/626,535
Filed by Shimadzu Corporation, Kyoto (JP); and National Institute of Advanced Industrial Science and Technology, Tokyo (JP)
PCT Filed Jul. 19, 2019, PCT No. PCT/JP2019/028418
§ 371(c)(1), (2) Date Jan. 12, 2022,
PCT Pub. No. WO2021/014487, PCT Pub. Date Jan. 28, 2021.
Prior Publication US 2022/0260527 A1, Aug. 18, 2022
Int. Cl. G01N 27/62 (2021.01); H01J 49/00 (2006.01); H01J 49/02 (2006.01); H01J 49/42 (2006.01); H01J 49/16 (2006.01); H01J 49/24 (2006.01); H01J 49/40 (2006.01)
CPC G01N 27/62 (2013.01) [H01J 49/0036 (2013.01); H01J 49/0068 (2013.01); H01J 49/025 (2013.01); H01J 49/424 (2013.01); H01J 49/164 (2013.01); H01J 49/24 (2013.01); H01J 49/40 (2013.01)] 8 Claims
OG exemplary drawing
 
1. An ion analyzer for analyzing product ions generated by irradiating precursor ions derived from a sample component with radicals, the ion analyzer comprising:
a reaction chamber;
a radical supply unit configured to generate the radicals and supply the radicals to the reaction chamber;
a radical temperature acquisition unit configured to acquire a temperature of the radicals to be supplied to the reaction chamber from the radical supply unit;
a standard substance supply unit configured to supply a predetermined amount of predetermined precursor ions to the reaction chamber, the predetermined precursor ions being generated from a standard substance whose activation energy of a reaction in which the radicals attach to the standard substance is known;
an ion measurement unit configured to measure an amount of predetermined product ions generated from the precursor ions derived from the standard substance by the reaction with the radicals;
a reactive radical amount calculation unit configured to obtain, based on the amount of the predetermined product ions measured, an amount of reactive radicals that are radicals having an energy equal to or more than the activation energy among the radicals supplied to the reaction chamber; and
a radical density calculation unit configured to obtain a radical density based on the temperature of the radicals, the activation energy, and the amount of the reactive radicals.