	US 12,031,182 B2
	Differential diagnosis of eczema and psoriasis
Kilian Eyerich, Munich (DE); Carsten Schmidt-Weber, Munich (DE); and Bettina Knapp, Prien a. Chiemsee (DE)
Assigned to HELMHOLTZ ZENTRUM MÜNCHEN— DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH), Neuherberg (DE); and KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITÄT MÜNCHEN, Munich (DE)
Filed by HELMHOLTZ ZENTRUM MÜNCHEN—DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH), Neuherberg (DE); and KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITÄT MÜNCHEN, Munich (DE)
Filed on May 31, 2019, as Appl. No. 16/428,411.
Application 16/428,411 is a division of application No. 15/304,364, abandoned, previously published as PCT/EP2015/058149, filed on Apr. 15, 2015.
Claims priority of application No. 14164807 (EP), filed on Apr. 15, 2014.
Prior Publication US 2019/0316201 A1, Oct. 17, 2019
Int. Cl. C12Q 1/6883 (2018.01); C07K 16/18 (2006.01); C07K 16/22 (2006.01); C07K 16/24 (2006.01); C07K 16/28 (2006.01); C07K 16/40 (2006.01); G01N 33/68 (2006.01)

CPC C12Q 1/6883 (2013.01) [C07K 16/24 (2013.01); C07K 16/40 (2013.01); G01N 33/6881 (2013.01); C07K 16/18 (2013.01); C07K 16/22 (2013.01); C07K 16/244 (2013.01); C07K 16/2866 (2013.01); C12Q 2600/112 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/16 (2013.01); G01N 2800/205 (2013.01)]

20 Claims

1. A kit for quantifying the expression of protein from a set of genes in a sample, or a subset thereof, wherein the set of genes is the group consisting of CCL27, NOS2, IL36G, KLK13, SOST, NPTX1, PLA2G4D, GDA, IL36A, TGM1, CLEC4G, IL13, TCN1, TMPRSS11D and RHCG, comprising means for quantifying the expression of protein from at least a subset of the genes consisting of a CCL27 gene and a NOS2 gene, and wherein said means for quantifying expression of the CCL27 gene and means for quantifying expression of the NOS2 gene are antibodies, or fragments thereof, that specifically bind to CCL27 protein and to NOS2 protein, respectively.