CPC C12N 15/113 (2013.01) [A61K 9/0019 (2013.01); A61K 31/47 (2013.01); A61K 31/713 (2013.01); A61K 38/1709 (2013.01); A61K 48/0058 (2013.01); C07K 14/4702 (2013.01); C07K 14/4746 (2013.01); C07K 14/82 (2013.01); C12N 5/0657 (2013.01); C12N 15/1135 (2013.01); C12N 15/86 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01); C12N 2320/31 (2013.01); C12N 2501/60 (2013.01); C12N 2710/10043 (2013.01); C12N 2740/15043 (2013.01)] | 18 Claims |
1. A composition for reprogramming differentiated cardiac cells to cardiomyocyte-like cells, the composition comprising one or more nucleic acid vectors, said vectors comprising one or more agents that inactivates p63 and comprising one or more cardiac cell reprogramming factors, wherein the cardiac cell reprogramming factors comprise Hand2 nucleic acids and myocardin nucleic acids.
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