US 12,030,961 B2
Method for removing organic solvent from starch hemostatic microspheres
Yang Fu, Zhejiang (CN); Jie Li, Zhejiang (CN); and Zhongyi Chen, Zhejiang (CN)
Assigned to Hangzhou Singclean Medical Products Co., Ltd, Hangzhou (CN)
Filed by Hangzhou Singclean Medical Products Co., Ltd, Zhejiang (CN)
Filed on Sep. 20, 2021, as Appl. No. 17/479,586.
Claims priority of application No. 202011547512.1 (CN), filed on Dec. 24, 2020.
Prior Publication US 2022/0204652 A1, Jun. 30, 2022
Int. Cl. C08B 30/06 (2006.01); A61L 15/28 (2006.01); A61L 15/42 (2006.01); B01D 53/04 (2006.01); F26B 7/00 (2006.01)
CPC C08B 30/06 (2013.01) [A61L 15/28 (2013.01); A61L 15/42 (2013.01); B01D 53/0407 (2013.01); F26B 7/00 (2013.01); A61L 2400/04 (2013.01); B01D 2253/202 (2013.01)] 2 Claims
OG exemplary drawing
 
1. A method for removing an organic solvent from starch hemostatic microspheres, comprising the following steps:
(1) laying the starch hemostatic microspheres flatly on drying trays;
(2) taking an adsorbent according to a mass ratio of 20% to 100% of the starch hemostatic microspheres, packaging the adsorbent into dialyzing paper bags, and sealing the dialyzing paper bags, wherein the adsorbent is an adsorbent capable of adsorbing organic gases contained in the starch hemostatic microspheres; and
(3) placing the drying trays loaded with the starch hemostatic microspheres obtained in step (1) and the sealed dialyzing paper bags obtained in step (2) within a low-temperature vacuum oven in layers, setting the oven temperature at 0-20° C., then vacuumizing the oven to a negative pressure of −0.1 to −0.05 MPa, and keeping the pressure of −0.1 to −0.05 MPa within the oven for 15-48 hours.