US 12,029,744 B2
Bicyclic heteroaryl derivatives as ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors
Ronald Hawley, Palo Alto, CA (US); and Klaus Klumpp, Palo Alto, CA (US)
Assigned to Riboscience LLC, Palo Alto, CA (US)
Appl. No. 17/264,684
Filed by Riboscience LLC, Palo Alto, CA (US)
PCT Filed Apr. 10, 2020, PCT No. PCT/US2020/027700
§ 371(c)(1), (2) Date Jan. 29, 2021,
PCT Pub. No. WO2020/210649, PCT Pub. Date Oct. 15, 2020.
Claims priority of provisional application 62/833,455, filed on Apr. 12, 2019.
Claims priority of provisional application 62/881,111, filed on Jul. 31, 2019.
Prior Publication US 2022/0362266 A1, Nov. 17, 2022
Int. Cl. C07F 5/02 (2006.01); A61K 31/675 (2006.01); A61K 31/683 (2006.01); A61K 31/69 (2006.01); A61K 45/06 (2006.01); C07F 9/6503 (2006.01); C07F 9/6506 (2006.01)
CPC A61K 31/69 (2013.01) [A61K 31/675 (2013.01); A61K 31/683 (2013.01); A61K 45/06 (2013.01); C07F 5/027 (2013.01); C07F 9/65038 (2013.01); C07F 9/65068 (2013.01)] 40 Claims
 
1. A compound selected from the group consisting of:

OG Complex Work Unit Chemistry

OG Complex Work Unit Chemistry
or
a pharmaceutically acceptable salt thereof.