US 12,029,627 B2
Intranasal administration device
Gershon Goldenberg, Pardes Hanna-Karkur (IL); Asaf Halamish, Pardes Hanna-Karkur (IL); Yehuda Ehud Ashash, Sede Nahum (IL); and Avner Finger, Pardes Hanna-Karkur (IL)
Assigned to pHi-Tech Animal Health Technologies Ltd., Airport City (IL)
Filed by pHi-Tech Animal Health Technologies Ltd., Airport City (IL)
Filed on Jun. 8, 2020, as Appl. No. 16/895,790.
Application 16/895,790 is a continuation of application No. PCT/IB2018/059883, filed on Dec. 11, 2018.
Claims priority of provisional application 62/596,967, filed on Dec. 11, 2017.
Prior Publication US 2020/0297467 A1, Sep. 24, 2020
Int. Cl. A61D 7/00 (2006.01); A61D 1/02 (2006.01); A61M 15/08 (2006.01)
CPC A61D 7/00 (2013.01) [A61D 1/025 (2013.01); A61M 15/08 (2013.01)] 24 Claims
OG exemplary drawing
 
1. An intranasal administration device, comprising:
a hand-held unit comprising a gripping portion and a spray head, the spray head comprising a spray apparatus and a nozzle configured to administer a discrete dose of medicament in aerosolized form, the nozzle comprising a soft cone configured to fit within a nostril of a non-human patient to prevent dispersion of a spray outside the nostril and to direct spray through the nostril toward an inner tissue, the spray head being removably coupled to the gripping portion;
a control unit, fluidly coupled to the hand-held unit via one or more flexible connecting tubes configured to resist widening upon a passage of medicament therethrough;
one or more containers for holding at least one medicament, the one or more containers being removably coupled to the control unit;
at least one pump located within the control unit, the pump configured to pump medicament from the control unit to the spray apparatus, the pump comprising (i) a first non-return valve, which allows the discrete dose of medicament to pass from the one or more containers to the pump but prevents backflow from the pump to the one or more containers, and (ii) a second non-return valve, which allows the discrete dose of medicament to pass from the pump to the hand-held unit but prevents backflow from the hand-held unit to the pump, wherein the pump comprises a piston, the piston being coupled to an encoder for positioning the piston head to determine a medicament dosage; and
a mechanism for adjusting spray droplet size of the medicament in aerosolized form.