US 12,029,572 B2
Method of estimating a system response of an individual listener's brain to a sound signal stimulus
Ivine Kuruvila, Erlangen (DE); Ulrich Hoppe, Spardorf (DE); Stefan Handrick, Erlangen (DE); Eghart Fischer, Schwabach (DE); Maja Serman, Erlangen (DE); and Henning Puder, Erlangen (DE)
Assigned to Sivantos Pte. Ltd., Singapore (SG)
Filed by Sivantos Pte. Ltd., Singapore (SG)
Filed on Nov. 30, 2020, as Appl. No. 17/106,442.
Claims priority of application No. 19212300 (EP), filed on Nov. 28, 2019.
Prior Publication US 2021/0161418 A1, Jun. 3, 2021
Int. Cl. A61B 5/377 (2021.01); A61B 5/291 (2021.01); A61B 5/316 (2021.01); A61B 5/374 (2021.01)
CPC A61B 5/377 (2021.01) [A61B 5/291 (2021.01); A61B 5/316 (2021.01); A61B 5/374 (2021.01)] 18 Claims
OG exemplary drawing
 
1. A method of estimating a system response of an individual listener's brain to a sound signal stimulus, the system response representing a generation of an electroencephalography signal measured at a given measuring point of the listener's head by the sound signal stimulus, the method comprising:
presenting a first sound signal containing the sound signal stimulus to an ear of the listener;
generating a first audio signal corresponding to the first sound signal, and extracting first audio signal data from the first audio signal;
using a first measuring electrode at said given measuring point on the listener's head for measuring a first electroencephalography training signal while the first sound signal containing the sound signal stimulus impinges on the ear of the listener, and generating a first measurement data set from the first electroencephalography training signal;
using a noise measuring electrode at a noise measuring point on the listener's head for measuring a noise signal while the first sound signal impinges on the ear of the listener, and generating a noise data set from the noise signal;
deriving from the first measurement data set and the noise data set a Gaussian conditional probability density function for the system response of the listener's brain to the first audio signal data, given an observation of the first measurement data set; and
taking the Gaussian conditional probability density function as the system response of the listener's brain to the sound signal stimulus, with respect to the given measurement point.