US 12,029,571 B2
Methods and devices for providing a parameter that indicates a higher likelihood of a postoperative delirium occurring
Susanne Koch, Berlin (DE); and Claudia Spies, Berlin (DE)
Assigned to COVIDIEN LP, Mansfield, MA (US)
Appl. No. 17/252,113
Filed by Covidien LP, Boulder, CO (US)
PCT Filed Jun. 17, 2019, PCT No. PCT/EP2019/065832
§ 371(c)(1), (2) Date Dec. 14, 2020,
PCT Pub. No. WO2019/238974, PCT Pub. Date Dec. 19, 2019.
Claims priority of application No. 102018114364.8 (DE), filed on Jun. 15, 2018.
Prior Publication US 2021/0321928 A1, Oct. 21, 2021
Int. Cl. A61B 5/374 (2021.01); A61B 5/00 (2006.01); G01R 23/15 (2006.01); G16H 10/60 (2018.01); G16H 50/20 (2018.01); G16H 50/70 (2018.01)
CPC A61B 5/374 (2021.01) [A61B 5/7271 (2013.01); G16H 10/60 (2018.01); G16H 50/70 (2018.01); G01R 23/15 (2013.01); G16H 50/20 (2018.01)] 20 Claims
OG exemplary drawing
 
1. A method for providing a parameter that indicates a heightened likelihood of postoperative delirium occurring, wherein the method comprises:
receiving at least one electroencephalography (EEG) signal from a head of a patient, wherein the at least one EEG signal is received within a period of time in which the patient is under anesthesia;
filtering the at least one EEG signal to produce at least one filtered EEG signal, wherein the at least one filtered EEG signal comprises a reduced total amount of frequencies compared to a total amount of frequencies of the at least one EEG signal;
determining an intraoperative alpha peak frequency of the at least one filtered EEG signal, wherein the intraoperative alpha peak frequency is a frequency in an alpha band of the at least one filtered EEG signal at which a power is greatest;
determining a difference value between the intraoperative alpha peak frequency and a preset reference value associated with the heightened likelihood of postoperative delirium; and
providing the parameter that indicates the heightened likelihood of postoperative delirium occurring based on the difference value being greater than a preset difference value.