CPC A61B 5/150755 (2013.01) [A61B 5/15003 (2013.01); A61B 5/150099 (2013.01); A61B 5/150274 (2013.01); A61B 5/150351 (2013.01); A61B 5/150389 (2013.01); A61B 5/150473 (2013.01); A61B 5/154 (2013.01); B01L 3/5082 (2013.01); G01N 33/491 (2013.01); A61B 5/1438 (2013.01); A61B 5/150503 (2013.01); B01L 3/505 (2013.01)] | 14 Claims |
1. A blood collection unit for coagulating whole blood for subsequent autologous or allogeneic use, comprising:
an outer wall comprising a closed bottom end, an open top end, a side wall spanning between the ends to form an inside surface, and a stopper inserted into the open top end to releasably seal the blood collection unit, the stopper having a puncturable self-sealing septum or valve;
an inner volume of the blood collection unit defined within the outer wall between the closed bottom end and the stopper,
wherein the inner volume is pressurized at a coagulation accelerating vacuum of at least 90% so that coagulation of blood in the blood collection unit is accelerated;
a coagulation activation site disposed in the inner volume of the blood collection unit and that has an uncoated surface with a roughness, RRMS, of at least 0.012 μm, and
an insertable insert disposed in the inner volume of the blood collection unit,
wherein the coagulation activation site is formed on the insertable insert.
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