US 12,029,381 B2
Devices and methods for treating skin tissue using cold plasma
Moshe Azoulay, Kibbutz Megido (IL); and Eliezer Fuchs, Kibbutz Megido (IL)
Assigned to Inbar Medical Ltd., Sofia (BG)
Filed by Inbar Medical Ltd., Sofia (BG)
Filed on Sep. 10, 2020, as Appl. No. 17/016,837.
Claims priority of application No. 20182205 (EP), filed on Jun. 25, 2020.
Prior Publication US 2021/0401480 A1, Dec. 30, 2021
Int. Cl. A61B 18/14 (2006.01); A45D 29/00 (2006.01); A45D 44/00 (2006.01); A61B 18/04 (2006.01); A61B 17/00 (2006.01); A61B 18/00 (2006.01)
CPC A61B 18/042 (2013.01) [A45D 29/00 (2013.01); A45D 44/00 (2013.01); A45D 2200/20 (2013.01); A61B 2017/00172 (2013.01); A61B 2017/0046 (2013.01); A61B 2018/0047 (2013.01); A61B 2018/0072 (2013.01); A61B 2018/00767 (2013.01); A61B 2018/0091 (2013.01)] 19 Claims
OG exemplary drawing
 
1. A system for treating skin and nails with cold plasma, the system comprising a discharge device, which comprises a handle and an applicator, and control infrastructure, which comprises a waveform generator;
wherein the applicator comprises an elongated tube, extending from a tube proximal end to a tube distal end, and a cathode housed within the tube, the tube being mounted, via the tube proximal end, on a distal tip portion of the handle;
wherein the handle comprises a flyback amplifier functionally associated with the waveform generator and electrically associated with the cathode, the waveform generator being configured to induce the flyback amplifier to apply a voltage at the cathode;
wherein the voltage produced by the flyback amplifier is configured to allow generating a self-sustaining Townsend avalanche when the tube distal end is positioned sufficiently near a target site on a skin surface or a nail of a subject, such as to produce a cold plasma discharge directed at the target site, the cold plasma discharge having an average electrical current amplitude in the range of about 0.1 mA to about 10 mA and an average power in the range of about 0.1 μW to about 10 μW, the system being thereby configured to treat the target site without heating thereof; and
wherein the tube distal end is open and configured to be pressed against skin of a subject around a target site, such as to fluidly seal the tube distal end, wherein the control infrastructure further comprises a vacuum pump fluidly coupled to the tube via an applicator gas port on the tube proximal end, such as to allow withdrawing gas from the tube, and wherein, optionally, the cathode comprises a needle extending longitudinally within the tube.