CPC G01N 33/54386 (2013.01) [G01N 21/64 (2013.01); G01N 21/78 (2013.01); G01N 24/088 (2013.01); G01N 33/487 (2013.01); G01N 33/5308 (2013.01); G01N 33/54306 (2013.01); G01N 33/6803 (2013.01); G01R 33/323 (2013.01); G01N 21/6489 (2013.01); G01N 2021/6495 (2013.01); G01N 2021/7783 (2013.01); G01N 2570/00 (2013.01)] | 20 Claims |
1. A method for measuring a concentration of label-free target molecules in a sample fluid, the method comprising:
exposing a substrate to a sample fluid such that a plurality of capture reagents attached to a surface of the substrate contact the sample fluid, the plurality of capture reagents including first capture reagents configured to bind to first label-free target molecules and second capture reagents configured to bind to second label-free target molecules different from the first label-free target molecules;
detecting, based on emission of electromagnetic radiation from at least one color center within the substrate, a change in a property of the at least one color center in response to binding between the first label-free target molecules and the first capture reagents; and
determining, based on the detected change, a concentration of the first label-free target molecules within the sample fluid.
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