CPC G01N 33/4915 (2013.01) [B01L 3/50273 (2013.01); B01L 3/502761 (2013.01); G01N 15/1056 (2013.01); G01N 33/5014 (2013.01); G01N 33/585 (2013.01); B01L 2200/0647 (2013.01); B01L 2400/0436 (2013.01); G01N 2015/142 (2013.01); G01N 2510/00 (2013.01)] | 10 Claims |
1. A cell-sorting system comprising:
a flow cell for flowing a sample comprising microbubble-labeled cells and unlabeled cells, wherein the flow cell comprises one or more inlet channels, a flow channel having an upstream portion, upstream of one or more acoustic transducers relative to a direction of sample flow through the flow channel, and a downstream portion, downstream of the one or more acoustic transducers relative to a direction of sample flow through the flow channel, and one or more outlet channels; and
the one or more acoustic transducers acoustically coupled with the flow cell, wherein the one or more acoustic transducers is positioned and configured to deliver a traveling acoustic wave through the flow channel to apply an acoustic radiation force to a sample flowing through the flow channel such that the microbubble-labeled cells are displaced relative to unlabeled cells along a direction of the acoustic radiation force away from the one or more acoustic transducers, the direction of the acoustic radiation force being transverse to the direction of sample flow.
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