CPC C07K 16/2851 (2013.01) [C07K 16/2803 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01)] | 13 Claims |
1. A method for treating a subject having osteoporosis and bone erosion, the method comprising administering an anti-NKG2A antibody, or an antigen binding fragment thereof to said subject, wherein said antibody blocks inhibitory signaling by CD94-NKG2A receptors and is a non-depleting antibody, and wherein said antibody has a heavy chain comprising the CDR1, CDR2 and CDR3 of SEQ ID NO: 2 and a light chain comprising the CDR1, CDR2 and CDR3 of SEQ ID NO: 3, or wherein said antibody has a heavy chain comprising the CDR1, CDR2 and CDR3 of SEQ ID NO: 4 and a light chain comprising the CDR1, CDR2 and CDR3 of SEQ ID NO: 5.
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