CPC C07K 14/705 (2013.01) [C07K 14/52 (2013.01); C07K 14/5437 (2013.01); G01N 33/57492 (2013.01); A61K 38/00 (2013.01); C07K 2319/01 (2013.01); C07K 2319/06 (2013.01); C07K 2319/09 (2013.01); C07K 2319/30 (2013.01); C07K 2319/33 (2013.01); C07K 2319/55 (2013.01); C07K 2319/74 (2013.01)] | 28 Claims |
1. A nucleic acid that encodes a polypeptide construct having a formula from N terminus to C terminus of: F-G-H, or H-G-F
wherein: F is a ligand that binds to all three of EphA2, EphA3 and EphB2; G is a peptide linker; and H is a ligand that binds to IL-13Rα2.
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