US 11,697,638 B2
5-methoxy-N,N-dimethyltryptamine crystalline forms
Peter Rands, London (GB); and Marie Claire Layzell, London (GB)
Assigned to Small Pharma Ltd, London (GB)
Filed by Small Pharma Ltd, London (GB)
Filed on Sep. 8, 2021, as Appl. No. 17/469,063.
Prior Publication US 2023/0086574 A1, Mar. 23, 2023
Int. Cl. C07D 209/16 (2006.01)
CPC C07D 209/16 (2013.01) [C07B 2200/05 (2013.01); C07B 2200/13 (2013.01)] 19 Claims
 
1. A crystalline fumarate salt of a compound having a Formula I :

OG Complex Work Unit Chemistry
wherein:
each R1 is independently selected from protium and deuterium;
each R2 is independently selected from protium and deuterium;
each R3 is independently selected from protium and deuterium; and
each R4 is independently selected from protium and deuterium; and
wherein the crystalline fumarate salt has a PXRD pattern comprising characteristic peaks at 19.2±0.2 and 24.7±0.2 degrees 2-theta.