US 11,696,895 B2
Fine particle coating (drug-containing hollow particle and method for manufacturing same)
Takumi Asada, Suita (JP); and Mitsuaki Kobiki, Kobe (JP)
Assigned to Sumitomo Pharma Co., Ltd., Osaka (JP)
Appl. No. 16/959,017
Filed by Sumitomo Pharma Co., Ltd., Osaka (JP)
PCT Filed Oct. 18, 2018, PCT No. PCT/JP2018/038895
§ 371(c)(1), (2) Date Jun. 29, 2020,
PCT Pub. No. WO2019/130749, PCT Pub. Date Jul. 4, 2019.
Claims priority of application No. JP2017-254309 (JP), filed on Dec. 28, 2017.
Prior Publication US 2020/0338010 A1, Oct. 29, 2020
Int. Cl. A61K 9/50 (2006.01)
CPC A61K 9/5089 (2013.01) [A61K 9/501 (2013.01); A61K 9/5015 (2013.01); A61K 9/5026 (2013.01); A61K 9/5047 (2013.01)] 8 Claims
OG exemplary drawing
 
1. A method of manufacturing hollow particles coated with coatable microparticles, comprising:
mixing the coatable microparticles with an inner core comprising a component of interest and a macromolecule such that a mixture is obtained; and
performing coating while rolling the mixture and while spraying a solvent that has a property of dissolving the macromolecule, such that hollow particles including the component of interest and coated with the coatable microparticles are obtained,
wherein the inner core has a shell and a hollow section.