US 11,696,707 B2
Tunable hybrid III-V/IV laser sensor system-on-a chip for real-time monitoring of a blood constituent concentration level
Augustinas Vizbaras, Vilnius (LT); Kristijonas Vizbaras, Vilnius (LT); Ieva Simonyte, Vilnius (LT); and Günther Roelkens, Schellebelle (BE)
Assigned to Brolis Sensor Technology, UAB et al., Vilnius (LT)
Filed by Brolis Sensor Technology, UAB, Vilnius (LT); Universiteit Gent, Ghent (BE); and IMEC VZW, Leuven (BE)
Filed on Aug. 15, 2022, as Appl. No. 17/887,974.
Application 17/887,974 is a continuation of application No. 16/609,355, previously published as PCT/EP2018/063260, filed on May 21, 2018.
Claims priority of provisional application 62/595,283, filed on Dec. 6, 2017.
Claims priority of provisional application 62/539,759, filed on Aug. 1, 2017.
Claims priority of provisional application 62/509,301, filed on May 22, 2017.
Prior Publication US 2023/0036048 A1, Feb. 2, 2023
Int. Cl. A61B 5/145 (2006.01); A61B 5/1455 (2006.01); G01N 21/39 (2006.01); H01S 5/026 (2006.01); H01S 5/125 (2006.01); H01S 5/20 (2006.01)
CPC A61B 5/1455 (2013.01) [G01N 21/39 (2013.01); A61B 2562/0238 (2013.01); H01S 5/026 (2013.01); H01S 5/125 (2013.01); H01S 5/20 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A wearable device for optical sensing physiological properties of a subject wearing the wearable device, the wearable device comprising:
an optical-interface shaped for contact with a subject, the optical-interface member configured to handle optical energy for sensing of one or more physiological properties of the subject;
a power supply member in power-communication with i) electronic components of the wearable device and ii) photonic components of the wearable device;
one or more processors supplied power by the power supply, the one or more processors configured to process digital signals of the wearable device; and
a silicon or silicon nitride transmitter photonic integrated circuit (PIC), the transmitter PIC comprising:
an array of cells, each cell comprising a laser-based sensor system-on-a-chip for real-time monitoring of at least one of the one or more physiological properties of the subject, the system-on-a-chip comprising:
a tunable hybrid III-V/IV laser sensor, wherein during use the laser sensor is in communication with the optical-interface, and the optical interface is in optical communication with the subject,
wherein each array cell is targeted at a different spectral region and/or a separate target molecule, and
wherein a wavelength swept laser signal of each array cell is emitted at a different time and signal collection is realized by a synchronized detection with a single photodiode.