US 12,352,711 B2
System and method for magnetic resonance mapping of physical and chemical changes in conducting structures
Alexej Jerschow, New York, NY (US); Andrew J. Ilott, Belle Mead, NJ (US); Mohaddese Mohammadi, Brooklyn, NY (US); Emilia Silletta, Cordoba (AR); and Konstantin Romanenko, New York, NY (US)
Assigned to NEW YORK UNIVERSITY, New York, NY (US)
Filed by NEW YORK UNIVERSITY, New York, NY (US)
Filed on Mar. 4, 2024, as Appl. No. 18/595,333.
Application 18/595,333 is a continuation of application No. 16/434,168, filed on Jun. 6, 2019, granted, now 11,921,067.
Application 16/434,168 is a continuation in part of application No. PCT/US2017/064948, filed on Dec. 6, 2017.
Application 16/434,168 is a continuation in part of application No. 15/785,284, filed on Oct. 16, 2017, granted, now 10,712,297, issued on Jul. 14, 2020.
Application PCT/US2017/064948 is a continuation in part of application No. PCT/US2016/027624, filed on Apr. 14, 2016.
Claims priority of provisional application 62/431,075, filed on Dec. 7, 2016.
Claims priority of provisional application 62/149,159, filed on Apr. 17, 2015.
Prior Publication US 2024/0248052 A1, Jul. 25, 2024
This patent is subject to a terminal disclaimer.
Int. Cl. G01N 24/08 (2006.01); G01N 24/10 (2006.01); G01R 31/36 (2020.01); G01R 33/56 (2006.01)
CPC G01N 24/08 (2013.01) [G01N 24/10 (2013.01); G01R 31/3644 (2013.01); G01R 33/5602 (2013.01); G01R 33/5608 (2013.01)] 20 Claims
OG exemplary drawing
 
1. A system, comprising:
a conducting structure disposed in a magnetic field;
a detection medium external to the conducting structure; and
one or more processors configured to:
excite nuclear or electronic spins within the detection medium using an electromagnetic signal having a first frequency;
receive an electromagnetic signal having a second frequency from the detection medium;
obtain a first distribution of frequencies of the detection medium at a first time and a second distribution of frequencies of the detection medium at a second time different from the first time, the first distribution of frequencies different from the second distribution of frequencies;
detect frequency changes between the first distribution of frequencies of the detection medium and the second distribution of frequencies of the detection medium to obtain internal characteristics of the conducting structure; and
model the internal characteristics of the conducting structure on the basis of current distributions within the conducting structure, the modeling on the basis of current distributions within the conducting structure comprising:
assigning one or more regions within the conducting structure a given current distribution; and
calculating a generated magnetic field based on an effect on the detection medium,
wherein amplitudes of current distributions of the one or more regions form parameters configured to be fit by minimizing differences between a calculated frequency distribution and a measured frequency distribution in the detection medium.