US 12,352,622 B2
Smartphone-based OCT systems and methods
Audrey K. Bowden, Nashville, TN (US); and Joseph D. Malone, Nashville, TN (US)
Assigned to Vanderbilt University, Nashville, TN (US)
Filed by Vanderbilt University, Nashville, TN (US)
Filed on Mar. 31, 2023, as Appl. No. 18/194,582.
Claims priority of provisional application 63/326,188, filed on Mar. 31, 2022.
Prior Publication US 2023/0314123 A1, Oct. 5, 2023
Int. Cl. G01J 3/02 (2006.01); A61B 5/00 (2006.01); G01B 9/02091 (2022.01); G01J 3/28 (2006.01); G02B 5/02 (2006.01); G06T 5/80 (2024.01); H04M 1/02 (2006.01)
CPC G01J 3/0208 (2013.01) [A61B 5/0066 (2013.01); G01B 9/02091 (2013.01); G01J 3/2803 (2013.01); G02B 5/0278 (2013.01); G06T 5/80 (2024.01); H04M 1/0202 (2013.01); G06T 2207/10024 (2013.01); G06T 2207/10101 (2013.01); G06T 2207/30024 (2013.01)] 9 Claims
OG exemplary drawing
 
1. A smartphone-integrated optical coherence tomography system comprising:
an optical coherence tomography (OCT) system including
a dispersion element positioned upstream of the smartphone, the dispersion element configured to receive relayed light from the sample and spectrally disperse the relayed light to generate a dispersed beam, and
a lens group positioned to receive and focus the dispersed beam to generate a spectrum;
a smartphone configured to receive a light signal from the OCT system, the light signal generated by reflection from a sample, the smartphone configured to generate OCT B-scans in real-time of the sample based on the light signal; and
a reverse-lens optically coupled to the OCT system and configured to receive the spectrum from the lens group and deliver the light signal to the smartphone;
wherein the smartphone generates RAW video data based on the spectrum of the sample, and
wherein the smartphone includes an application stored as non-transitory computer-readable medium, the application configured to
receive the RAW video data of the sample,
process the RAW video data for intensity correction and distortion correction, and
display, on the smartphone, a processed OCT B-scan of the sample.