US 12,351,664 B2
Thermally crosslinked poly(glucuronic acid)-chitosan films with high oxygen and water vapor barrier properties
James Carson Meredith, III, Atlanta, GA (US); and Chinmay Satam, Atlanta, GA (US)
Assigned to GEORGIA TECH RESEARCH CORPORATION, Atlanta, GA (US)
Appl. No. 17/765,287
Filed by GEORGIA TECH RESEARCH CORPORATION, Atlanta, GA (US)
PCT Filed Sep. 30, 2020, PCT No. PCT/US2020/053432
§ 371(c)(1), (2) Date Mar. 30, 2022,
PCT Pub. No. WO2021/067372, PCT Pub. Date Apr. 8, 2021.
Claims priority of provisional application 62/908,009, filed on Sep. 30, 2019.
Prior Publication US 2022/0356286 A1, Nov. 10, 2022
Int. Cl. B29C 70/02 (2006.01); C08F 251/02 (2006.01); C08J 3/24 (2006.01); C08J 5/18 (2006.01)
CPC C08F 251/02 (2013.01) [C08J 3/246 (2013.01); C08J 5/18 (2013.01); C08F 2810/20 (2013.01); C08J 2301/02 (2013.01); C08J 2305/08 (2013.01); C08J 2371/02 (2013.01)] 19 Claims
 
1. A method of making a poly(alkylene glycol)-chitosan-poly(glucuronic acid) film; comprising:
contacting cellulose with NaOH and poly(alkylene glycol) to form a solution comprising poly(alkylene glycol), NaOH and cellulose;
contacting the solution comprising poly(alkylene glycol) and cellulose with 2,2,6,6-tetramethylpiperidine-1-oxyl radical and an oxidizing reagent to form a solution comprising poly(glucuronic acid) and poly(alkylene glycol);
separating any 2,2,6,6-tetramethylpiperidine-1-oxyl radical, oxidizing reagent, and cellulose from the solution comprising poly(glucuronic acid) and poly(alkylene glycol);
contacting the solution comprising poly(glucuronic acid) and poly(alkylene glycol) with an acidic solution of chitosan to form a solution comprising chitosan, poly(glucuronic acid), and poly(alkylene glycol);
casting or coating the solution comprising chitosan, poly(glucuronic acid), and poly(alkylene glycol) into a film; and
heating the film to crosslink the poly(glucuronic acid) with the chitosan and yield a poly(alkylene glycol)-chitosan-poly(glucuronic acid) film.