US 12,351,605 B2
Optically controllable FGFR stimulation using wireless controlled cellular lighting system
Gabsang Lee, Ellicott City, MD (US); Hyesoo Kim, Baltimore, MD (US); InYoung Choi, Baltimore, MD (US); HoTae Lim, Baltimore, MD (US); and Alex V. Huynh, Baltimore, MD (US)
Assigned to The Johns Hopkins University, Baltimore, MD (US)
Filed by THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US)
Filed on Jan. 19, 2021, as Appl. No. 17/152,220.
Claims priority of provisional application 62/962,246, filed on Jan. 17, 2020.
Prior Publication US 2021/0221858 A1, Jul. 22, 2021
Int. Cl. C07K 14/405 (2006.01); C07K 14/71 (2006.01); C12M 1/00 (2006.01); C12N 5/0735 (2010.01); C12N 5/074 (2010.01); C12N 13/00 (2006.01)
CPC C07K 14/405 (2013.01) [C07K 14/71 (2013.01); C12M 31/10 (2013.01); C12N 5/0606 (2013.01); C12N 5/0696 (2013.01); C12N 13/00 (2013.01); C07K 2319/02 (2013.01)] 17 Claims
 
1. A vector comprising a nucleotide sequence encoding a fusion protein comprising the intracellular domain of fibroblast growth factor 1 receptor (FGFR1) and a photoactivatable domain, wherein the vector comprises the nucleotide sequence of SEQ ID NO: 1.