| CPC A61N 5/1037 (2013.01) [A61B 6/482 (2013.01); A61N 5/1049 (2013.01); A61B 6/025 (2013.01); A61B 6/4035 (2013.01); A61B 6/5223 (2013.01); A61B 6/583 (2013.01); A61N 2005/1061 (2013.01); A61N 2005/1062 (2013.01); A61N 5/1067 (2013.01); A61N 5/1083 (2013.01)] | 22 Claims |

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1. A method of image-guided radiation, the method comprising:
processing a first set of volumetric image data of a target and a second set of volumetric image data of the target to generate an enhanced image, wherein the first set of volumetric image data and the second set of volumetric image data include an overlapping portion of the target and respective non-overlapping portions of the target, and wherein generating the enhanced image comprises processing the first set of volumetric image data in conjunction with the second set of volumetric image data to perform a weighted combination of the overlapping portion on a voxelwise basis;
registering the enhanced image with another image to obtain a registration result;
tracking the target using the registration result to generate tracking information; and
directing treatment delivery to the target based on the tracking information obtained from the enhanced image.
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