US 12,350,489 B2
Electrode leads having nerve cuffs and associated systems and methods
Christopher Reed Jenney, Valencia, CA (US); Oren Gotlib, Agoura Hills, CA (US); Joseph Calderon, Santa Clarita, CA (US); William Andrew Brandt, Castaic, CA (US); and Neil Talbot, La Crescenta, CA (US)
Assigned to The Alfred E. Mann Foundation for Scientific Research, Valencia, CA (US)
Filed by The Alfred E. Mann Foundation for Scientific Research, Valencia, CA (US)
Filed on Mar. 1, 2022, as Appl. No. 17/683,598.
Claims priority of provisional application 63/167,756, filed on Mar. 30, 2021.
Prior Publication US 2022/0313987 A1, Oct. 6, 2022
Int. Cl. A61N 1/05 (2006.01); A61N 1/36 (2006.01); A61N 1/375 (2006.01); H01R 13/52 (2006.01)
CPC A61N 1/0556 (2013.01) [A61N 1/3752 (2013.01); H01R 13/5224 (2013.01); A61N 2001/0578 (2013.01); H01R 2201/12 (2013.01)] 6 Claims
OG exemplary drawing
 
1. An electrode lead, comprising:
an elongate lead body having a proximal end and a distal end; and
a nerve cuff including;
a biologically compatible, elastic, electrically insulative cuff body affixed to the distal end of the lead body, the cuff body being configured to be circumferentially disposed around a nerve, having a pre-set furled state that defines an inner lumen, being movable to an unfurled state, including front and rear layers, and defining a length, a length direction, a width in the unfurled state that is greater than the length, and a width direction,
first and second relatively wide electrically conductive members located between the front and rear layers of the cuff body, spaced from one another in the length direction, and extending in the width direction to such an extent that they extend completely around the cuff body inner lumen when the cuff body is in the pre-set furled shape,
the cuff body front layer including a plurality of openings that are spaced from one another in the width direction and are aligned with, and located inwardly of the perimeter of, the first relatively wide electrically conductive member and a plurality of openings that are spaced from one another in the width direction and are aligned with, and located inwardly of the perimeter of, the second relatively wide electrically conductive member,
a plurality of relatively narrow electrically conductive members located between the front and rear layers of the cuff body, spaced from one another in the width direction, and located between the first and second relatively wide electrically conductive members,
the cuff body front layer including a plurality of openings that are spaced from one another in the width direction and are respectively aligned with the relatively narrow electrically conductive members, and
a plurality of electrical conductors extending through the lead body from at least some of the electrically conductive members to the proximal end of the lead body.